Glenmark

Glenmark Pharmaceuticals is a multinational pharmaceutical company.It is headquartered in Mumbai, India. It makes a wide range of pharmaceutical products comprising different therapeutic areas such as respiratory, dermatology, cardiovascular, and many more. Gracias Saldanha established the company in 1977 as a producer of generic medications and active pharmaceutical ingredients.

Glenmark has also made large investments in the field of digital health and has introduced several ground-breaking healthcare technologies, including platforms for remote patient monitoring and medication adherence.

We’ll go into details about this company in this article. 

Company Overview

The corporate headquarters of the pharmaceutical company Glenmark Pharmaceuticals is in Mumbai, India. Glenmark is a global company with operations in over 80 nations. It offers a comprehensive range of branded and generic pharmaceuticals, including treatments for cardiovascular, pulmonary, oncological, and dermatological illnesses.

Glenmark has facilities in India, Switzerland, and the United States, and it has a significant emphasis on research and development. The company’s pipeline contains several novel medication candidates, and it has obtained regulatory approval for many of its drugs in a variety of markets.

Glenmark has also made large investments in the field of digital health and has introduced several ground-breaking healthcare technologies. The company has won multiple awards for its work in research and development and is regarded as one of India’s innovative companies.

Glenmark Pharmaceuticals has made news as a significant pharmaceutical firm for several different reasons over the years. The generic version of Pfizer’s Celebrex (celecoxib) pills, which are used to treat osteoarthritis, rheumatoid arthritis, and other disorders, was tentatively approved by the U.S. FDA in February 2022, according to Glenmark.

 Glenmark declared in August 2021 that it has signed a licensing agreement with Swiss pharmaceutical company Helsinn Group for the sole marketing and distribution of Helsinn’s cancer treatment Akynzeo in India and Nepal.

For the treatment of mild to moderate COVID-19 infections, Glenmark reported in June 2021 that a combination of the medications Favipiravir and Umifenovir has been given regulatory approval in India.

 Glenmark declared in January 2021 that the Indian pharma regulator had given the go-ahead for their novel antiviral medication, FabiFlu, which was administered to COVID-19 patients in India.

 Favipiravir, an antiviral medication, was introduced by Glenmark in August 2020 for the treatment of mild to moderate COVID-19 infections in India.

What Does Glenmark Sell?

Glenmark has strived to enhance patient lives all across the world. Glenmark has concentrated on developing a global innovative/specialty, generics, and OTC business in the treatment areas of dermatology, respiratory, and oncology to achieve this purpose. It also has a significant regional or national presence in other therapeutic fields like oral contraceptives, diabetes, and cardiovascular disease. 

Here are some of its popular products

Dermatology

Deriva CMS

Deriva CMS is a skincare product that is marketed by Glenmark Pharmaceuticals.It combines the topical retinoid Adapalene with the topical antibiotic Clindamycin. Deriva CMS is recommended for the treatment of acne vulgaris, a typical skin disorder that develops when oil and dead skin cells block hair follicles.

Adapalene helps to clear clogged pores and inhibit the development of new acne lesions, whereas Clindamycin works by halting the growth of acne-causing bacteria. Deriva CMS is a successful treatment for moderate to severe acne since it contains these two active components.

It is significant to remember that Deriva CMS may not be appropriate for everyone and should only be used as prescribed by a healthcare expert. It is crucial to review the risks and advantages with a healthcare professional before using this medicine because it has potential adverse effects, such as skin peeling, skin irritation, dryness, itching, and others.

Candid K

Candid K is a topical cream that is marketed by Glenmark Pharmaceuticals. It contains clotrimazole and beclomethasone dipropionate, two of its active components.

Athlete’s foot, jock itch, and ringworm are all fungal infections that are treated with the antifungal drug clotrimazole. It relieves symptoms including itching, burning, and scaling by inhibiting the growth of fungus.

A corticosteroid drug called beclomethasone dipropionate is used to lessen swelling and irritation brought on by various skin disorders, including eczema, psoriasis, and dermatitis.

It is recommended to use Candid K to treat various fungal skin infections, including candidiasis, a condition in which fungi infect the mouth, throat, or genitals. In Candid K, clotrimazole and beclomethasone dipropionate work together to treat the fungal infection as well as the swelling and itching that go along with it. It should be used under the direction of a physician. 

Inbilt 5

Inbilt 5 is a topical solution that contains minoxidil as its active ingredient. It is advertised for the treatment of androgenetic alopecia, a prevalent kind of hair loss in both men and women, and is distributed by Glenmark Pharmaceuticals. Genetic and hormonal factors contribute to androgenetic alopecia, which causes a gradual loss of scalp hair.

Inbilt 5 is applied topically on the scalp. To boost blood flow to the hair follicles and maybe stimulate hair growth, it works by enlarging the blood vessels in the scalp. The active growth phase of the hair follicle, known as the anagen phase of hair development, is thought to be prolonged by minoxidil.

Usually, Inbuilt 5 is applied twice daily to the scalp where hair is thinning. It is crucial to take the medication as prescribed and to take it regularly. Like other medicines, Inbilt 5 has potential adverse effects, so it’s crucial to consider the advantages and disadvantages with a doctor before using it.

Glencet

Glencet is a medication marketed by Glenmark Pharmaceuticals that contains Levocetirizine as its active ingredient. Levocetirizine is a second-generation antihistamine. It is used to treat a variety of allergic diseases such as hay fever, allergic rhinitis, and urticaria (hives).

Levocetirizine acts by inhibiting the effects of histamine, a substance the body releases in response to allergens. Many of the signs and symptoms of allergic reactions, including itchiness, sneezing, runny nose, and watery eyes, are brought on by histamine. Levocetirizine can assist to alleviate these symptoms and enhance the quality of life by inhibiting the effect of histamine.

Glencet is used to treat several allergic diseases, such as allergic rhinitis and chronic idiopathic urticaria. It can be taken with or without food and is normally taken only once per day. 

Dosetil

Dosetil is a medication marketed by Glenmark Pharmaceuticals that contains Clobetasol Propionate as its active ingredient.

It is a topical steroid that is used to treat eczema, psoriasis, and dermatitis, among other skin problems. Clobetasol Propionate works by reducing inflammation and suppressing the immune system in the affected area. This can enhance the appearance of the skin and ease symptoms including itching, redness, and swelling.

As instructed by a healthcare practitioner, Dosetil is normally applied to the afflicted area of the skin once or twice daily. The risk of adverse effects can be increased by using the medication differently from how it is prescribed or for longer periods on larger areas of skin.

It shouldn’t be applied to the face, groin, or underarms unless a doctor specifically instructs you to.

Chronic

Telma

Telma contains Telmisartan as its active ingredient and is marketed by Glenmark Pharmaceuticals. It is a type of drug known as an angiotensin II receptor blocker (ARB), which is prescribed to treat hypertension or high blood pressure.

Telmisartan functions by preventing the hormone angiotensin II from constricting blood vessels. It helps to relax blood vessels and lower blood pressure by preventing the effect of this hormone, which can minimize the risk of cardiovascular events like heart attack or stroke.

According to medical advice, Telma is normally given once daily. It can be used either on its own or in conjunction with other drugs to treat excessive blood pressure. Like other medicines, Telma has potential negative effects, therefore it’s crucial to examine the advantages and disadvantages with a doctor before using it. It’s critical to follow the drug instructions and visit a doctor frequently to have your blood pressure checked and to check for any side effects that might be present.

Zita Met Plus

Zita Met Plus is a combination medication marketed by Glenmark Pharmaceuticals. Sitagliptin and Metformin are its two main active components. Sitagliptin is an oral diabetes drug that raises the body’s levels of a group of hormones known as incretins. By encouraging the release of insulin and limiting the amount of glucose the liver produces, these hormones aid in controlling blood sugar levels. The oral anti-diabetic drug metformin also lowers the quantity of glucose generated by the liver and increases insulin sensitivity in the body.

Type 2 diabetes, which develops when the body is unable to effectively utilize insulin or produce enough insulin to regulate blood sugar levels, is treated with Zita Met Plus. Usually, it is taken with meals twice a day. Depending on personal characteristics like age, weight, and general health, the dosage and length of the treatment may change.

Zita Met Plus, like all drugs, has potential adverse effects, therefore it’s crucial to evaluate the risks and advantages with a healthcare professional before using it. Nausea, diarrhea, headaches, and hypoglycemia are a few of the medication’s potential side effects. It’s critical to follow the prescription instructions and visit a doctor frequently to have your blood sugar levels checked and to discuss any side effects that might be present.

Respiratory

Ascoril

Ascoril contains three active ingredients: Salbutamol, Guaifenesin, and Bromhexine. It is produced by Glenmark Pharmaceuticals. It is a combination drug used to treat bronchitis, asthma, and chronic obstructive pulmonary disease (COPD), among other respiratory diseases.

Salbutamol is a type of drug known as a bronchodilator that increases airflow to the lungs by relaxing the muscles in the airways. An expectorant like guaifenesin acts by loosening and thinning mucus in the airways, which facilitates coughing. A mucolytic drug called bromhexine makes the mucus easier to evacuate from the respiratory tract by dissolving it.

Ascoril is normally taken orally under the guidance of a healthcare provider as a syrup or tablet. Depending on the patient’s condition and pharmaceutical reaction, the dosage and length of the course of treatment may change.

Some possible side effects of the medication may include nausea, vomiting, headache, dizziness, and tremors.

Oncology+Critical

Bortrac

Bortrac is a name of a medication that contains bortezomib as its active ingredient. It is produced by Glenmark Pharmaceuticals. It is a proteasome inhibitor and is used to treat multiple myeloma, a kind of cancer that affects plasma cells.

Bortezomib functions by preventing the breakdown of proteins in cells by proteasomes, which are biological components. Bortezomib can kill cancer cells by causing an accumulation of proteins in the cells as a result of the proteasomes’ inhibition.

Progressive multiple myeloma, a kind of multiple myeloma that has persisted after prior treatment, is treated with the drug Bortrac. Intravenous infusion is the common method of administration. Depending on a person’s unique circumstances, including the cancer’s stage and general health, the dosage and length of the course of treatment may change.

Like all medicines, Bortrac has potential adverse effects, so it’s crucial to consider the advantages and disadvantages with a doctor before using it. Low blood cell counts, lethargy, nausea, vomiting, and diarrhea are a few potential side effects of the medicine. It’s crucial to take the medication exactly as prescribed and to follow up with a healthcare professional frequently to track how the treatment is working and any potential adverse effects.

Glenmark Review: Comparing The Good & The Bad

Glenmark Pharmaceuticals is a leading Indian pharmaceutical company that has been in operation for over 40 years. It has a strong focus on research and development, has a global presence, has a diverse product portfolio, and is sustainable. However, the company has also undergone controversies due to its drug pricing and instances of product recall. It may help the company if it invests in new and more effective medications, improves its transparency as well as enhances its sustainability efforts. 


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