Cenforce Professional is a drug used to treat erectile dysfunction (ED). Sildenafil citrate serves as the foundational component of this drug. It is a phosphodiesterase 5 inhibitor and aids ED-afflicted males in achieving an erection. Treatment of benign prostatic hyperplasia can also benefit from it.
You must understand what Cenforce Professional is, what it does, and how to use it before using it. In this article, we’ll discuss these details.
What is Cenforce Professional?
A medication called Cenforce Professional is used to treat erectile dysfunction. Sildenafil, a highly effective erectile dysfunction drug, is its main constituent. It belongs to the group of drugs known as phosphodiesterase-5 (PDE5) inhibitors.
Cenforce Professional inhibits Phosphodiesterase Type 5 (PDE5), an enzyme that is mainly present in the penis. This enables it to generate an erection by relaxing the smooth muscles in the penis. By doing this, the penis’ corpora cavernosa region’s arteries’ blood flow will increase. The erections last a lot longer as a result.
The multinational pharmaceutical company Centurion Laboratories, with its headquarters in India, creates Cenforce Professional.
What’s The Dose of Cenforce Professional?
Cenforce Professional is available in the dosage of 100mg sublingual tablets. It comes as ten blue-colored tablets in one blister pack.
To take this drug, place the tablet under the tongue until it is dissolved. Take it about an hour before engaging in sexual activity. One pill per day is the suggested dosage or as directed by your physician. Only use this medication as required. You need a prescription before you purchase this drug as it is prescribed only in most countries. It is not necessary to consume it every day.
Never take more than is recommended as doing so could have negative side effects. Never abruptly stop using this medication without first talking to your doctor.
How Long Does it Take Cenforce Professional To Kick In?
It takes Cenforce Professional between 15 and 30 minutes to start working. For new users, this time frame can be a little bit longer. In this case, waiting for a time is advisable.
How Long Does Cenforce Professional Last?
After ingestion, Cenforce Professional lasts for roughly two to three hours. It might be a little bit longer in some circumstances, especially if you consume foods that will slow down Cenforce Professional’s metabolism.
How Much Does Cenforce Professional Cost?
It costs about 0.18 USD per tablet. Compared to other erectile dysfunction drugs, this is relatively inexpensive.
The History of Cenforce Professional
To understand how Cenforce Professional came about, we must first dive back to the discovery of its base ingredient sildenafil. The active ingredient Sildenafil citrate was created as a potential cardiac drug back in 1989. It was developed in anticipation that it would be able to manage high blood pressure and angina. Its potential to generate erections in ED patients was unintentionally found, but it completely changed how this condition was managed.
After the drug’s formulation received a patent in 1996, the FDA approved the use of Sildenafil in 1998. Pfizer continued to create and sell it thereafter.
In 2019, the patent expired, making it possible for other companies to produce the medication at a lower cost using the same recipe. Centurion Laboratories started producing Cenforce Professional following the grant of this patent.
Who Should Take Cenforce Professional?
Cenforce Professional is prescribed to men who have ED. You must have a prescription from a licensed physician to take Cenforce Professional because it is a prescription-only medication. As it is a sublingual drug, placing this medicine under your tongue allows it to dissolve and enter your bloodstream through the tissue there.
Before recommending Cenforce Professional, your physician will examine you to rule out any underlying medical issues or drug interactions. If everything goes as planned, they will then administer this medication according to your requirements.
Cenforce Professional is not advised for usage by women or kids.
Depending on how your body responds to the medication, your doctor may change the dosage. If any severe adverse effects develop while taking this medication, you should stop taking it right once and seek emergency medical help.
Is Cenforce Professional Safe?
Cenforce Professional is generally well-tolerated by users. But like most medicines, it also has a specific set of side effects. People with cardiac conditions should either use Cenforce Professional with caution or completely avoid it, according to their doctor’s advice.
Common Side Effects of Cenforce Professional
- Backaches
- Chest discomfort or pain
- Cough
- Diarrhoea
- Dizziness
- Dry mouth
- Fatigue
- Flushing
- Headache
- Indigestion
- Muscle aches
- Nausea
- Pain in the extremities
- Priapism
- Stomach pain or upset
- Stuffy or runny nose
- Tingling sensation in the hands and feet
- Upper Respiratory Tract Infections
- Vision Disturbances
Potential Drug Interactions With Cenforce Professional
If Cenforce Professional is taken along with some particular medications, there may be a chance for drug interactions to happen. This could result in anything from minor side effects to serious and potentially fatal effects. If using Cenforce Professional with these drugs results in such negative effects, there is a probability that taking any other PDE5 inhibitor medicine will result in a similar interaction. If you want to avoid such side effects while taking Cenforce Professional with these specific medications, it is best to talk this up with your doctor beforehand.
Some of the common medications that can interact with Cenforce Professional are:
Nitrates
Drugs like amyl nitrate, nitroglycerin, isosorbide, nitroprusside, etc. are examples of nitrates. These medications are essential medications for heart disorders. Lowering blood pressure is one of these medications’ key characteristics. When combined with these medications, Cenforce Professional can significantly lower blood pressure.
Alcohol
Alcohol of any kind can have negative effects when combined with Cenforce Professional. Headaches, nausea, sleepiness, and low blood pressure are among the symptoms.
Guanylate Cyclase Stimulators
When combined with these medications, Cenforce Professional, which has its blood pressure-lowering ability, can work with them to reduce blood pressure levels to very low. These include medications like riociguat, a common medication recommended to treat pulmonary hypertension.
CYP3A4 Inhibitors
The active ingredient in Cenforce Professional, sildenafil, is metabolised by the CYP3A4 enzyme. Inhibitors of the CYP3A4 enzyme stop it from functioning. As a result, the two together can greatly slow down the body’s ability to rid itself of Cenforce Professional. As a result, the effects of Cenforce Professional last longer. Ritonavir, ketoconazole, itraconazole, erythromycin, and other drugs are CYP34A inhibitors.
Anti-Hypertensives
These medications and Cenforce Professional may interact, leading to a sudden and severe reduction in blood pressure. These drugs include, among others, calcium channel blockers, angiotensin II receptor blockers, ACE inhibitors, and alpha-blockers.
CYP3A4 Stimulants
These drugs counteract the effects of CYP3A4 inhibitors. They shorten Cenforce Professional’s half-life and speed up its metabolism in the body. Rifampin, carbamazepine, phenytoin, phenobarbital, and other medications fall within this category.
Antacids
Antacids can decrease the body’s ability to absorb Cenforce Professional, which can decrease its effectiveness. Among these are drugs like Alternagel, Amphojel, Alka-Seltzer, Tums, Gelusil, Maalox, Mylanta, and Rolaids.
Who Should Avoid Using Cenforce Professional
- Patients diagnosed with retinitis pigmentosa
- Patients taking any of the contraindicated medications listed in the previous section
- Patients with a history of NAION or “crowded” optic disc
- Patients with a history of priapism
- Patients with a hypersensitivity to Cenforce Professional
- Patients with certain blood disorders (haemophilia, leukaemia, sickle-cell anaemia)
- Patients with severe heart disease or heart valve failure
- Patients with severe kidney disease
How Does Cenforce Professional Work
The main component of Cenforce Professional is sildenafil. It belongs to the group of drugs called phosphodiesterase 5 inhibitors.
It functions by boosting blood flow in the arteries feeding the corpora cavernosa, the region of the penis where erections occur. The corpora cavernosa, platelets, skeletal muscles, and vascular, and visceral muscles are the tissues where PDE5 is most frequently found.
Normally, after sexual stimulation, the nerves in the pelvic area become active. Nitric oxide (NO) will then start to travel through and around the smooth muscles of the corpora cavernosa and penile arteries. Cyclic guanosine monophosphate is generated in greater quantities by nitric oxide (cGMP). The corpora cavernosa and smooth muscles of the penile relax as a result, and blood flow to the penis also increases. As a result of this, an erection occurs.
In ED patients, these arteries are frequently damaged and dysfunctional. PDE5 prevents cGMP from operating normally in ED patients, which prevents the smooth muscles of the penis from relaxing. The penis consequently doesn’t get enough blood flow. As a result, no erection occurs.
The sildenafil in this drug helps one get an erection following sexual stimulation. Its activity results in an erection, which significantly raises the level of genital blood in the bloodstream.
Medical Research Involving Cenforce Professional
The sildenafil component of Cenforce Professional is useful for treating pulmonary hypertension and erectile dysfunction [1,2]. Though some research has been done on the sildenafil in this medication, there hasn’t been a lot of research done by specific companies. This is because there is no need for independent research since all companies produce the pharmaceuticals using the same generic formula.
Best Cenforce Professional Alternatives
To treat ED, a wide variety of medicines are available. They might contain additional components or a substance that has a similar outcome to the primary ingredient in Cenforce Professional. But in the end, they can all produce an erection.
Pharmaceutical Alternatives
There are various alternatives to Cenforce Professional. Some of these may be more reasonably priced than others. But they all carry out the same tasks.
The following commercial drugs have similar effects to Cenforce Professional:
- Sildenafil (Viagra, Cenforce, Kamagra, Fildena, P-Force, Vygex, & more)
- Tadalafil (Cialis, Adcirca, Vidalista, Tadacip, Forzest, & more)
- Avanafil (Avaforce, Stendra, Avana)
- Mirodenafil (Mvix)
- Udenafil (Zydena)
- Vardenafil (Levitra, Staxyn, Vilitra, Zhewitra, Savitra, & more)
Natural Cenforce Professional Alternatives
Cenforce Professional has a few natural alternatives as well. They include numerous vitamins and herbs. However, the majority of them lack enough clinical testing and research to back up their efficacy.
However, if you are afraid to take pharmaceutical medications alone, these complementary and alternative remedies might be a great place to start. You can then switch to using pharmaceutical drugs if these don’t work.
The following additional herbs and vitamins can be used to treat ED:
Tongkat Ali — Tongkat Ali is a herb that can improve vitality and assist treat ED and impotence [3].
Horny goat weed (Epimedium spp.) — The icariin enzyme produced by horny goat weed shows comparable PDE5 inhibition properties to Cenforce Professional. Joint discomfort, impotence, and poor libido can all be treated with horny goat weed [4].
Ginseng (Panax ginseng) — This herb may help manage blood sugar levels, strengthen the immune system, enhance cognitive function, and minimise fatigue in addition to treating ED [5].
Muira puama (Ptychopetalum olacoides) — This herb, Muira puama, can decrease the symptoms of ED and increase sex drive [6]. The corpora cavernosa, which acts as a sponge and retains blood during an erection, is relaxed by this herb. Because of the increased blood flow to the penis caused by this relaxation, the erectile response is improved.
L-arginine — This amino acid produces nitric oxide. Following that, ED may benefit from the NO’s production of cGMP [7].
Catuaba (Trichilia catigua or Erythroxylum Catuaba) — ED and low libido may be treated with catuaba [8]. Furthermore, they can improve sexual prowess.
Yohimbe (Pausinystalia johimbe) — This herb has been demonstrated to lessen ED symptoms and heighten sexual contact [9]. Yohimbine is believed to cure erectile dysfunction by inhibiting the receptors that interfere with erections. Nitric oxide may be released more quickly as a result of yohimbine. Penile erections could develop from the blood vessels in the penis expanding as a result.
Where to Buy Cenforce Professional in 2022
You need a prescription from your doctor to take Cenforce Professional. Once you’ve obtained the prescription, you can purchase it online or from any neighbourhood pharmacy. Since buying online is more private and convenient than going shopping, it is recommended.
Because there are less expensive generic alternatives available, it is advised to shop around and choose the drug that is best for you.
Cenforce Professional can be your best option for treating erectile dysfunction.
References Cited in This Article
- Hatzimouratidis, K. (2006). Sildenafil in the treatment of erectile dysfunction: an overview of the clinical evidence. Clinical interventions in aging, 1(4), 403.
- Barnett, C. F., & Machado, R. F. (2006). Sildenafil in the treatment of pulmonary hypertension. Vascular health and risk management, 2(4), 411.
- Kotirum, S., Ismail, S. B., & Chaiyakunapruk, N. (2015). Efficacy of Tongkat Ali (Eurycoma longifolia) on erectile function improvement: Systematic review and meta-analysis of randomized controlled trials. Complementary therapies in medicine, 23(5), 693-698.
- Liu, W. J., Xin, Z. C., Xin, H., Yuan, Y. M., Tian, L., & Guo, Y. L. (2005). Effects of icariin on erectile function and expression of nitric oxide synthase isoforms in castrated rats. Asian journal of andrology, 7(4), 381-388.
- De Andrade, E., De Mesquita, A. A., de Almeida Claro, J., De Andrade, P. M., Ortiz, V., Paranhos, M., … & Erdogrun, T. (2007). Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction. Asian journal of andrology, 9(2), 241-244.
- Ferrini, M. G., Garcia, E., Abraham, A., Artaza, J. N., Nguyen, S., & Rajfer, J. (2018). Effect of ginger, Paullinia cupana, Muira puama, and l-citrulline, singly or in combination, on modulation of the inducible nitric oxide-NO-cGMP pathway in rat penile smooth muscle cells. nitric oxide, 76, 81-86.
- Moody, J. A., Vernet, D., Laidlaw, S., Rajfer, J., & Gonzalez-Cadavid, N. F. (1997). Effects of long-term oral administration of L-arginine on the rat erectile response. The journal of urology, 158(3), 942-947.
- Lim, P. H. (2017). Asian herbals and aphrodisiacs are used for managing ED. Translational andrology and urology, 6(2), 167.
- Carey, M. P., & Johnson, B. T. (1996). Effectiveness of yohimbine in the treatment of erectile disorder: Four meta-analytic integrations. Archives of sexual behavior, 25(4), 341-360.
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