Kamagra Oral Jelly

Kamagra Oral Jelly is the brand name of the generic drug sildenafil citrate. Its use is in the treatment of erectile dysfunction.

This article will explain everything you need to know before using Kamagra Oral Jelly. We will talk about what it is, what it does, its origins, and what you can expect from it.

Let’s jump right into it.

What is Kamagra Oral Jelly?

Kamagra Oral Jelly is used to treat erectile dysfunction (ED). Its active ingredient is sildenafil citrate, the base ingredient in another popular ED medication, Viagra.

The jelly is a product of Ajanta Pharma Ltd, a pharmaceutical company established in 1973 and located in Mumbai, India.

Kamagra Oral Jelly comes in sachets of 100 mg each. There are seven sachets in a pack.

The base ingredient, sildenafil, works by inhibiting an enzyme in the body called phosphodiesterase 5 (PDE5). Inhibiting this enzyme relaxes smooth muscles, increases blood flow into the penis, and causes an erection.

The main benefit of Kamagra Oral Jelly is that it can be scooped up by a spoon, eaten, and swallowed. So, it is beneficial for those who have trouble swallowing pills.

What’s the Dose of Kamagra Oral Jelly?

A single color-coded sachet of Kamagra Oral Jelly contains 100 mg of sildenafil citrate. The maximum dose is one sachet of 100 mg daily and on an as-needed basis.

It’s color-coded according to its flavor:

Pineapple
Orange
Strawberry
Vanilla
Banana
Black currant
Butterscotch
Mint
Rose
Mango
Lemon
Cherry
Chocolate
Watermelon
Guava
Litchi
Raspberry
Green apple
Caramel
Kiwi

It’s a prescription-only medication in most countries, so you need a certified doctor’s prescription to buy it.

How Long Does It Take for Kamagra Oral Jelly to Kick In?

Kamagra Oral Jelly starts to work in about 30 to 60 minutes. However, it may take a little longer than that for some patients. If you’re a first-time user and the jelly is taking too long to work, it may be a good idea to wait a bit longer.

However, like most ED medications, there is a small catch — it cannot work on their own. You have to be sexually excited for it to work. It won’t trigger an erection.

How Long Does Kamagra Oral Jelly Last?

Once taken, Kamagra Oral Jelly lasts for almost 3 hours. Its half-life is 3 to 5 hours. Its effect may be quite long, nearly 24 hours in some men.

How Much Does Kamagra Oral Jelly Cost?

Kamagra oral jelly costs about $3.33 to $6 per jelly. This price is slightly less costly than other medications for ED.

The History of Kamagra Oral Jelly

Sildenafil citrate, the active ingredient used to make Kamagra Oral Jelly, was developed as a heart and high blood pressure medication back in 1989. Researchers at Pfizer discovered by accident that it can induce erections.

However, this discovery changed the whole course of treatment for ED. For the first time, men suffering from ED had a proper drug to treat their condition precisely and easily.

The formula was patented in 1996 and approved by the FDA in 1998.

The patent for sildenafil ended in 2019, and many companies started producing it at a lower cost. Ajanta Pharma Ltd started producing Kamagra Oral Jelly after the end of this patent.

Who Should Take Kamagra Oral Jelly?

Your doctor may prescribe Kamagra Oral Jelly if you have problems maintaining an erection during sex. It is a prescription-only medication used primarily to treat ED.

Before prescribing this, your doctor will see if you have any underlying health conditions or if your current medications could interact with this drug.

Is Kamagra Oral Jelly Safe?

Kamagra Oral Jelly is generally safe to take in most men. Like most other medications, it has some side effects, some of which could be severe.

One of the main reasons these side effects can happen is if a person takes more than the recommended dose or uses it irresponsibly.

Common Side Effects of Kamagra include:

Headaches (21% of users)
Flushing (19% of users)
Indigestion (9% of users)
Vision Loss (2% of users)
Nasal congestion (4% of users)
Back pain (4% of users)
Dizziness (4% of users)
Abnormal vision (3%)
Nausea (3% of users)
Rash (2% of users)
Muscle pain (2% of users)

Potential Drug Interactions With Kamagra Oral Jelly

Like many other medications, some drugs can interact with Kamagra Oral Jelly and cause problematic side effects.

Tell your doctor beforehand if you take any of the following drugs:

Nitrates

These drugs treat angina and coronary artery disease and can cause a severe drop in blood pressure. These drugs include nitroglycerin, isosorbide, amyl nitrate, etc.

Guanylate Cyclase (GC) Stimulators

These drugs include medications like riociguat and are used in pulmonary hypertension treatment. Combining these two can cause a fast drop in blood pressure.

Anti-Hypertensive Medications

These include medications like alpha-blockers, angiotensin-converting enzyme (ACE) inhibitors, calcium channel blockers, and angiotensin II receptor blockers. Taking these and Kamagra Oral Jelly together can cause a rapid drop in blood pressure.

CYP3A4 Inhibitors

CYP3A4 is the enzyme that metabolizes sildenafil, Kamagra oral jelly’s base ingredient. Using them together can cause a delay in the removal of Kamagra Oral Jelly from the body, causing it to stay in the body for a much longer duration. These medications include ritonavir, ketoconazole, itraconazole, erythromycin, etc.

Alcohol

Kamagra Oral Jelly can react with alcohol, including wine, beer, and spirits, and cause excess symptoms of headaches, dizziness, low blood pressure, and increased heart rate.

Antacids

These include Alternagel, Amphojel, Alka-Seltzer, Tums, magnesium hydroxide, Gaviscon, Gelusil, Maalox, Mylanta, and Rolaids. These can react with Kamagra Oral Jelly and decrease its absorption rate, increasing the risk of side effects.

CYP3A4 Inducers

These work opposite to CYP3A4 inhibitors and can cause faster metabolism of Kamagra Oral Jelly, leading to shorter or less pronounced effects. These include Rifampin, Carbamazepine, Phenytoin, Phenobarbital, etc.

Who Should Avoid Using Kamagra Oral Jelly

Avoid Kamagra and let your doctor know if you have the following:

A history of NAION or “crowded” optic disc
A history of hypersensitivity to Kamagra Oral Jelly
A history of priapism
Certain blood disorders (hemophilia, leukemia, sickle-cell anemia)
Contraindicated medications listed in the previous section
Retinitis pigmentosa
Severe heart disease or heart valve failure
Severe kidney disease

How Does Kamagra Oral Jelly Work

Kamagra Oral Jelly’s active ingredient is sildenafil citrate, a phosphodiesterase 5 (PDE5) inhibitor. There are many different kinds of phosphodiesterase enzymes in the body. PDE5 is concentrated mainly in the corpora cavernosa, platelets, skeletal muscles, and visceral muscles but is most prominent in the penis.

Following sexual excitement, nerves are stimulated in the pelvic region. These nerve stimulations lead to nitric oxide (NO) release in the penile arteries and cavernous smooth muscles. NO increases the amount of cyclic guanosine phosphate (cGMP), which causes relaxation of the penile smooth muscles and corpus cavernosa. They also cause increased blood flow to the penis, leading to an erection.

In cases of ED, these blood vessels to the penis are affected and cannot work properly. PDE5 inhibits cGMP’s actions and causes a lack of relaxation of the penile muscles. This can cause poor proper blood flow into the penis, making it difficult to achieve an erection.

Kamagra Oral Jelly works against this by inhibiting the PDE5 enzyme. This allows blood vessels to relax and increases blood flow to the penis, resulting in an erection. It also maintains the erection long enough for you to have sex.

However, sexual stimulation is essential for Kamagra Oral Jelly to work. It cannot work on its own.

Medical Research Involving Kamagra Oral Jelly

Kamagra Oral Jelly has limited research to show its effectiveness in treating ED. This is because it is produced based on the formulation of sildenafil, which has been extensively researched.

For most medications, research is limited to the first patented formulation. Once the patent expires, other pharmaceutical companies can make the same drugs, usually at a much lower price.

Best Kamagra Oral Jelly Alternatives

Many medications can be used to treat ED. Many use the same active ingredient as Kamagra Oral Jelly, sildenafil. A few others use ingredients that are different from sildenafil but have a similar mechanism of action.

Pharmaceutical Alternatives

After the patent over sildenafil ended, various companies started making many forms of the same drug with the same ingredient as Kamagra oral jelly. Some of them may be cheaper, while others may be more expensive. But they all use the same kind of compound and have similar doses.

Other brands that work the same as Kamagra oral jelly include:

Avanafil (Avaforce, Stendra, Avana)
Miodenafil (Mvix)
Sildenafil (Viagra, Cenforce, Fildena, P-Force, Vygex, & more)
Tadalafil (Cialis, Adcirca, Vidalista, Tadacip, Forzest, & more)
Udenafil (Zydena)
Vardenafil (Levitra, Staxyn, Vilitra, Zhewitra, Savitra, & more)

Natural Kamagra Oral Jelly Alternatives

There are some traditional herbs and nutrients that can also help treat ED. These have long been used in traditional medicine; however, they lack sufficient research and evidence to show how well they can work.

If you are hesitant to try out the medical formulations, you can give these herbs a try. If they do not work, you can switch to prescription meds.

Here are some of the alternative herbs and nutrients that can help treat ED [8].

Horny goat weed (Epimedium spp.) — This herb has an enzyme called icariin that may inhibit PDE5 similar to Kamagra Oral Jelly [2].

Ginseng (Panax ginseng) — This is a herb native to Korea and is used as a sexual stimulant and may help in ED [3].

Muira puama (Ptychopetalum olacoides) — This is a herb native to the Amazon rainforests and might help treat impotence by acting as a sexual stimulant [4].

L-Arginine — It can increase cGMP by synthesizing nitric oxide and help initiate erections in people with ED [5].

Catuaba (Trichilia catigua or Erythroxylum Catuaba) — This herb is native to Asia and used to treat increase libido and help with ED and impotence [6].

Yohimbe (Pausinystalia johimbe) — Yohimbe can help treat ED as it works as an aphrodisiac [7].

Where to Buy Kamagra Oral Jelly?

Kamagra oral jelly is a prescription-only drug in most countries. This means you need to get a prescription from a licensed doctor to get this.

Once you get the prescription, you can buy Kamagra oral jelly from nearby pharmacies or online. The latter may be a better choice as it is easier, cheaper, and more discreet.

So if you are searching for an easy-to-swallow medication to treat your erectile dysfunction, Kamagra oral jelly may be the best medication for you.

References

Langtry, H. D., & Markham, A. (1999). Sildenafil. Drugs, 57(6), 967-989.
Liu, W. J., Xin, Z. C., Xin, H., Yuan, Y. M., Tian, L., & Guo, Y. L. (2005). Effects of icariin on erectile function and expression of nitric oxide synthase isoforms in castrated rats. Asian journal of andrology, 7(4), 381-388.
De Andrade, E., De Mesquita, A. A., de Almeida Claro, J., De Andrade, P. M., Ortiz, V., Paranhos, M., … & Erdogrun, T. (2007). Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction. Asian journal of andrology, 9(2), 241-244.
Ferrini, M. G., Garcia, E., Abraham, A., Artaza, J. N., Nguyen, S., & Rajfer, J. (2018). Effect of ginger, Paullinia cupana, muira puama and l-citrulline, singly or in combination, on modulation of the inducible nitric oxide-NO-cGMP pathway in rat penile smooth muscle cells. nitric oxide, 76, 81-86.
Moody, J. A., Vernet, D., Laidlaw, S., Rajfer, J., & Gonzalez-Cadavid, N. F. (1997). Effects of long-term oral administration of L-arginine on the rat erectile response. The journal of urology, 158(3), 942-947.
Lim, P. H. (2017). Asian herbals and aphrodisiacs used for managing ED. Translational andrology and urology, 6(2), 167.
Wibowo, D. N. S. A., Soebadi, D. M., & Soebadi, M. A. (2021). Yohimbine as a treatment for erectile dysfunction: A systematic review and meta-analysis. Turkish Journal of Urology, 47(6), 482-488.
Goel, B., & Maurya, N. K. (2020). Aphrodisiac Herbal therapy for Erectile Dysfunction. Archives of Pharmacy Practice, 11(1).