Noxitril: Everything You Should Know Before You Buy

The male-enhancement space is very large and diverse. Noxitril is just one of several hundred supplement brands promising dramatic improvements in libido and overall sexual performance. 

While we never recommend buying male performance enhancers online due to the sheer number of low-quality products in this space, Noxitril is carried by GNC — which is considered a reputable source of health supplements in North America. 

Nevertheless, it can be a daunting challenge for men to find a supplement that fits their budget, and offers a level of impact that matches their expectations. 

In this article, we’ll explore the Noxitril herbal male enhancement formula in-depth. We’ll cover what it is, what’s included in the formula, and how this supplement works. 

We’ll also cover some of the downsides and potential side effects to be aware of when using this supplement. 

What is Noxitril?

Noxitril is a blend of herbal extracts and nutrients designed to support male reproductive function. The website promoting this product is vague in the language used to describe the benefits of this supplement, stating that “Noxitril is designed to help you achieve more during sex, by improving your body in various key areas”. 

This description offers no insight into how the formula is designed to work. You won’t find any specific details about what the formula is meant to accomplish, or how it works on the official website. 

What Are the Benefits of Noxitril?

The main ingredients in the formula are tongkat ali, maca, ginseng, L-arginine — all of which are common ingredients in male-enhancement supplements. They’re used to promote erections naturally, support cardiovascular health, support testosterone production, and improve overall fertility.

None of these benefits are officially listed on the website, but could be derived from the formula. The only real benefit suggested by the website is “improving natural energy”. 

There are other ingredients in this formula as well, some of which have shown additional support for maintaining erections, promoting sperm production, balancing testosterone levels, and reducing prostate problems and male pattern balding. However, these other ingredients are offered at much lower dosages than the four main ingredients and likely only offer a supporting role. 

The name of the supplement suggests the formula is intended to boost nitric oxide production (NOX for short). NOX is an important part of maintaining an erection because it serves as the first chemical messenger that triggers the relaxation of the arteries supplying blood to the penis that leads to an erection. However, nothing about nitric oxide is mentioned anywhere on the website. 

The owner of Noxitril is unknown, and the address officially listed for the company appears to be a residential address in Los Angeles, California.

The website for this product consists of just one page, and was registered back in 2016. 

Noxitril Reviews: Does Noxitril Actually Work? 

The ingredients in Noxitril will work in theory, but the effects of a formula in real life may vary. 

Noxitril has been on the market for about four years now, and there are a lot of reviews for the supplement available on places like Amazon, Reddit, and various male enhancement forums. 

The response for this supplement is mixed — some users rave about the impact the supplement had for supporting a healthy erection, others were upset that the product didn’t work and complain about the quality of the customer service offered by the Noxitril team. 

There have also been over a dozen reports to the Better Business Bureau (BBB), claiming the company is misleading customers, and won’t follow through on its money-back guarantee. 

Overall, this product is hit or miss. You may find this supplement works very well for managing your erectile dysfunction, but it’s also completely possible it won’t do anything at all. 

Unfortunately, due to the issues with customer service for this company, we don’t recommend this brand. 

Instead, go for products from Nugenix or VigRX, which offer similar formulas, but have a much more reliable customer service team in the event the supplement doesn’t do what you expect. 

The Potential Side Effects of Noxitril

All supplements bring risk of side-effects. All the ingredients included in the Noxitril formula are generally regarded as safe. However, some of the ingredients, such as tongkat ali, may interact with other medications or underlying health issues. 

This company doesn’t list any specific warnings for its product on the website. 

Potential Side Effects of Noxitril Include: 

  • Increased heart rate
  • High blood pressure
  • Anxiety
  • Skin rashes or irritations
  • Insomnia
  • Indigestion
  • Nausea or vomiting
  • Headaches
  • Dizziness

What Are the Ingredients in Noxitril? How Do They Work?

Noxitril contains four primary ingredients, along with 13 supporting ingredients contained in what the company refers to as a ‘proprietary formula’. 

Let’s go over each ingredient in greater detail, highlighting how it works. 

1. Tongkat Ali

Tongkat ali is the first of the four primary ingredients in the formula. The botanical name for this herb is Eurycoma longifolia.

This herb has a long history of use for supporting male fertility and reproductive health. It’s used to boost low testosterone levels in older men, as an aphrodisiac, and much more.

A study done in 2012 involving 75 men diagnosed with testosterone deficiency were given 200 mg of tongkat ali extract for 30 days [1]. At the end of the study the testosterone levels improved significantly in 91% of the study participants. 

This is one of the primary ingredients in the formula, useful or supporting male reproductive health overall, especially in men with testosterone levels lower than normal. 

The dose of tongkat ali extract in this particular formula is 200 mg. 

2. Maca

Maca (Lepidium meyenii) is a root vegetable from the high Andean mountains in South America. Extracts of this herb are used to support male fertility and testosterone levels. 

This herb is rich in amino acids such as L-arginine that are required in the production of testosterone and nitric oxide. It’s through these nutritional benefits that maca is thought to offer benefits to the male reproductive system. 

A study published in 2002 explored the effects of maca for boosting libido in men [2]. Subjects were given either 1500 or 3000 mg of maca root or a placebo for 12 weeks. At the end of the trial, researchers reported a significant improvement in sexual desire in the treatment group, but no change in estrogen or testosterone levels compared to the placebo. These benefits weren’t noted until the 8th week of the study. 

The effects of maca are much more subtle than other herbs in this formula, and take a long time to produce results. The maximum benefit on male reproductive health from maca comes after using the herb consistently for several weeks at a time. 

3. L-Arginine

L-arginine is an amino acid found abundantly in nuts, dairy, and meat. It has a lot of different uses in the body as a building block for various proteins and enzymes. 

One of the most important uses of L-arginine is in the production of nitric oxide (NOX) [3]. Arginine serves as the base for nitric oxide, which goes on to trigger the cascade of effects involved with forming an erection. 

The goal behind supplementing L-arginine is to ensure enough of the raw ingredients to produce nitric oxide are available to the body to avoid erectile issues as a result of low nitric oxide production.

4. Ginseng Blend

There are two species of ginseng — Panax ginseng (Asian ginseng), and Panax quinquefolium (American ginseng). Both species contain a series of chemicals known as ginsenosides, which are a powerful class of cardiotonic and adaptogenic compounds. 

Noxitril doesn’t offer any details on what this blend consists of, but it’s assumed to mean the formula contains a blend of both ginseng species. 

Ginseng offers many indirect benefits for the male reproductive system. Studies have shown that ginseng can improve blood flow to the penis [4], supports sperm production [5], and improves energy levels [6]. 

5. Astragalus

This is the first of the ingredients listed on Noxitril under the ‘proprietary blend’, which means we have no idea how much astragalus is included in the formula. 

Astragalus (Astragalus membranaceus), isn’t commonly used in male reproductive formulas. It’s primarily used to support immune function. However, studies have shown that astragalus can be used to support sperm production and increase overall sperm count in men [7]. 

The benefits of astragalus on sperm production require several weeks of consistent use. 

6. Boron

Boron is a trace mineral involved in dozens of processes in the human body. It’s required for the formation of bone tissue, vitamin D production, cognitive health, and testosterone production. 

It’s unlikely boron itself will lead to higher testosterone levels unless the cause of the testosterone deficiency is low dietary boron intake. 

7. Catuaba

There are two different types of catuaba being marketed for male reproductive functions. Noxitril offers no insight into which species is being used in this formula. 

Most nutritional supplements use the species Erythroxylum catuaba, but another species, Trichilia catigua is also sometimes used. 

Both of these species are used interchangeably in the Amazon basin where they grow naturally. They’re used to support male fertility, improve erection status, and boost libido — especially in older men. 

8. Cayenne Pepper

Cayenne pepper acts as a circulatory stimulant. It causes blood vessels to dilate, allowing blood to flow into the deeper tissues fed by the microcapillary network. 

Spicy foods in general are often used by men to support vasodilation in the penis — leading to a stronger erection. 

There has only been a small number of studies investigating the benefits of spicy foods like cayenne pepper on improving erection status in men, but the results so far are promising [8]. 

9. Licorice

Licorice (Glycyrrhiza glabra) is a common herb in the traditional Chinese herbal medicine for supporting hormone levels and alleviating chronic stress. 

Compounds in licorice mimic some of the stress hormones in the body. Over time, these compounds increase the sensitivity of a region of the brain called the hypothalamus, which acts as the regulator for stress hormones in the body. 

When the hypothalamus is functioning optimally, levels of our stress hormone, cortisol, gradually start to decline. 

High cortisol is thought to be one of the primary causes for low libido, low testosterone levels, and erectile dysfunction in men [9].

10. Muira Puama

Muira puama (Ptychopetalum olacoides) is another plant species found in the Amazon rainforest. It’s often used alongside catuaba for supporting male reproductive health, as well as cognitive decline resulting from old age. 

There is very little research available on this herb so far, but it’s becoming more popular every year as a potential treatment for erectile dysfunction. 

One study looked at the effects of muira puama in combination with catuaba in a product called Catuama® [10]. The study found this formula caused a significant increase in nitric oxide production. 

11. Oat Straw

Oat straw is primarily used to support the nervous system in herbal medicine, but may also offer some improvements on male reproductive health too. 

This herb is very nutritious, offering over a dozen essential nutrients and minerals to the body — some of which are involved in testosterone and sperm production [11].

12. Orchic

Orchic is an extract obtained from bull testicles. It’s used in some circles as a sexual tonic, especially in Asia. It isn’t as popular as a health supplement in the Western world, and there are very few studies available that support its alleged health benefits. 

Most of the research on orchids involves animals, and many noted no statistically significant improvement in sexual function in the animals tested. 

13. Oyster Extract

Oyster extract is a rich source of zinc — which is essential in the production of testosterone in both men and women. It’s also required for cell division, which is a critically important process in the formation of sperm cells. 

Zinc has been shown to increase testosterone levels only in men who have zinc deficiencies [12]. 

14. Pumpkin Seed

Pumpkin seeds offer nutritional support for male reproductive health in two ways: 

  • They’re a rich source of zinc, which is important for the manufacture of testosterone
  • They’re rich in omega 3 fatty acids — which serve as the base ingredient for prostaglandins that are involved with erectile function and libido

The dose of pumpkin seeds in this formula is likely too low to offer any real benefit. The daily recommended dose of omega 3 is around 500 mg. The entire proprietary blend section of this supplement only contains 745 mg total, which is split among 13 separate ingredients. 

15. Sarsaparilla

Sarsaparilla (Smilax spp.) is a popular supplement among bodybuilders and athletes for its ability to support hormone production in men and women. However, to date, there have been no reputable studies involving humans that support this idea. 

16. Stinging Nettle

There are two parts of the stinging nettle herb used therapeutically for completely separate applications. 

The leaves of the plant are used for upper respiratory tract infections, inflammation, and allergies. 

The root of the plant is used for benign prostatic hyperplasia. This effect has a lot of research to back it up, but only when used in relatively high doses. 

Noxitril only lists “nettle (herb powder)” on the label, so we can’t be sure the herb the company uses is specifically stinging nettle (Urtica dioica), nor that the part of the herb being used is the roots. 

17. Tribulus

Tribulus (Tribulus terrestris) is one of the most popular herbs available for supporting the male reproductive system. It’s used for several different types of male reproductive dysfunctions, including poor libido, erectile dysfunction, infertility, and testosterone deficiency. 

The active ingredients in this herb are a group of saponins (mainly protodioscin). This compound has been shown to support nitric oxide production in the penis, leading to improvements in maintaining an erection [13]. 

Other studies support the use of tribulus extracts for increasing testosterone levels in men experiencing testosterone deficiencies. It works by increasing the release of gonadotropin from the brain [14], which goes on to stimulate the secretion of testosterone from the testes. 

How Much Does Noxitril Cost? 

On the official Noxitril website, the cost of the herbal formula is $89.95 for one bottle (1-month supply), $269.85 for 3 bottles (3-month supply), and $539.70 for 6 bottles (6-month supply). 

These are the ‘normal listed price’ — however, these products are on a perpetual ‘sale’. This is a common tactic companies use to make it seem like the product you’re buying is on sale to make it seem like you’re getting a better deal. In reality, the true cost of the supplement is the ‘sale’ price. 

The cost for these capsules on Amazon is the same as the sale price. GNC sells these capsules for $10 cheaper for one bottle ($59.99), but there are no bulk order discounts. 

Like most supplements, the more you order at a time the better the overall value. If you buy 6 months worth of Noxitril at a time, the cost per capsule is roughly half the cost compared to buying just one month’s supply. 

Noxitril Cost Breakdown

Order VolumeNumber of Capsules“Regular” PriceTrue Price (Sale Price)Cost Per Capsule
1 Month Supply (1 Bottle)60 Capsules$89.95$69.95$1.15 per Capsule
3 Month Supply (3 Bottles)180 Capsules$269.85$139.90$0.78 per Capsule
6 Month Supply (6 Bottles)360 Capsules$539.70$209.85$0.58 per Capsule

Noxitril Alternatives

Men experiencing problems with testosterone levels, erection, or fertility have many options to consider. Noxitril is just one of several hundred treatment options used to support male reproductive health. 

The best option depends on your budget, the source of the issue, and the severity of the condition. 

Herbal & Nutritional Supplements

Noxitril is just one example of the many natural male-enhancement formulas on the market today. You can find supplements that consist of single ingredients, all the way up to products like Extenze that offer dozens of compounds in the same formula. 

Here are some of the best alternatives to Noxitril for supporting sexual health in 

  1. Nugenix — best overall
  2. Andro400 — best for testosterone levels
  3. VigRX — best for erectile dysfunction
  4. Semenax — best for semen production

Prescription Erectile Dysfunction Medications

There are also prescription medications useful for supporting erectile dysfunction that can be considered. All ED medications are available by prescription only, so you’ll need to speak with your doctor to rule out potential health problems from using these drugs. 

Most men will find natural supplements like Noxitril, Nugenix, VigRX, or Andro400 offer enough support that prescription ED pills aren’t necessary. However, if these supplements don’t work, drugs like Viagra, Cialis, or Levitra are great alternatives to consider. 

The best prescription ED medications include:

  • Sildenafil (Viagra, Kamagra, Fildena)
  • Tadalafil (Cialis, Tadalista)
  • Avanafil (Stendra, Spedra)
  • Vardenafil (Levitra, Vivanza)

Non-Supplement Based Alternatives

There are a few options that don’t involve taking medications or supplements. Such as improving your diet to support natural testosterone production and fertility, using penis pumps to induce an erection, or having prosthetic implants installed in the penis to induce an erection at will. 

Even taking measures to improve the quality of your sleep or reduce stress levels can go a long way in promoting fertility, testosterone balance, and erectile function over time. 

Where Can I Buy Noxitril? 

Noxitril is available on the company’s official website,, as well as marketplaces such as Amazon, eBay, and GNC. 

If you’re only going to buy one bottle, it’s cheaper to order from GNC. However, if you want to get the best value for the money, you should order from the Noxitril website directly, and go for the larger volumes. If you get 6 months of this supplement at a time, it will only cost 58 cents per capsule, for a total cost of $1.16 per day. 


  1. Tambi, M. I. B. M., Imran, M. K., & Henkel, R. R. (2012). Standardised water‐soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late‐onset hypogonadism?. Andrologia, 44, 226-230.
  2. Gonzales, G. F., Córdova, A., Vega, K., Chung, A., Villena, A., Góñez, C., & Castillo, S. (2002). Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men. andrologia, 34(6), 367-372.
  3. Moncada, S., & Higgs, A. (1993). The L-arginine-nitric oxide pathway. New England Journal of Medicine, 329(27), 2002-2012.
  4. De Andrade, E., De Mesquita, A. A., de Almeida Claro, J., De Andrade, P. M., Ortiz, V., Paranhos, M., … & Erdogrun, T. (2007). Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction. Asian journal of andrology, 9(2), 241-244.
  5. Zhang, H., Zhou, Q., Li, X., Zhao, W., Wang, Y., Liu, H., & Li, N. (2007). Ginsenoside Re promotes human sperm capacitation through nitric oxide‐dependent pathway. Molecular Reproduction and Development: Incorporating Gamete Research, 74(4), 497-501.
  6. Reay, J. L., Kennedy, D. O., & Scholey, A. B. (2005). Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity. Journal of Psychopharmacology, 19(4), 357-365.
  7. Kim, W., Chang, M. S., & Park, S. K. (2016). Astragalus membranaceus augment sperm parameters in male mice associated with cAMP-responsive element modulator and activator of CREM in testis. Journal of traditional and complementary medicine, 6(3), 294-298.
  8. Lazzeri, M., Barbanti, G., Beneforti, P., & Turini, D. (1994). Intraurethrally infused capsaicin induces penile erection in humans. Scandinavian journal of urology and nephrology, 28(4), 409-412.
  9. Brownlee, K. K., Moore, A. W., & Hackney, A. C. (2005). Relationship between circulating cortisol and testosterone: influence of physical exercise. Journal of sports science & medicine, 4(1), 76.
  10. Antunes, E., Gordo, W. M., De Oliveira, J. F., Teixeira, C. E., Hyslop, S., & De Nucci, G. (2001). The relaxation of isolated rabbit corpus cavernosum by the herbal medicine Catuama® and its constituents. Phytotherapy Research, 15(5), 416-421.
  11. Lim, P. H. (2017). Asian herbals and aphrodisiacs used for managing ED. Translational andrology and urology, 6(2), 167.
  12. Prasad, A. S., Mantzoros, C. S., Beck, F. W., Hess, J. W., & Brewer, G. J. (1996). Zinc status and serum testosterone levels of healthy adults. Nutrition, 12(5), 344-348.
  13. Singh, S., Nair, V., & Gupta, Y. K. (2012). Evaluation of the aphrodisiac activity of Tribulus terrestris Linn. in sexually sluggish male albino rats. Journal of pharmacology & pharmacotherapeutics, 3(1), 43.
  14. Moghaddam, M. H. G., Khalili, M., Maleki, M., & Abadi, M. E. A. (2013). The effect of oral feeding of Tribulus terrestris L. on sex hormone and gonadotropin levels in addicted male rats. International journal of fertility & sterility, 7(1), 57.






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