Snovitra

Snovitra is a medication used in treating erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). It contains the base ingredient called vardenafil. 

The users who are planning to use Snovitra need to know the proper details and information about this drug before using it. This includes what it is, what it does, and how it can be consumed

We will explain the details of this medication in this article. 

What is Snovitra?

Snovitra is a generic vardenafil. It is used in treating erectile dysfunction (ED) in men. It is a phosphodiesterase type 5(PDE5) inhibitor. It is also useful in treating benign prostatic hyperplasia (BPH). 

ED is a common occurrence in men with older age and mental or physical health problems. This is usually due to some physiological or pathological condition that prevents blood flow into the erectile tissues of the penis, making it unable to become erect. 

Snovitra counters these conditions by inhibiting the abilities of the enzyme PDE5 and allowing enough blood to flow into the penis for it to get erect.

Snovitra is a product of Parex Pharmaceuticals, a pharmaceutical company based in India. 

What’s The Dose of Snovitra?

Snovitra comes in a dose of 20mg pills. These pills are small round shaped and yellow-colored and come in a blister pack of 10 tablets per pack.  

Snovitra may only be bought only with a prescription from a physician in the majority of countries. As a result, you must first have your physician examine your condition first.

It is advised to only use Snovitra when necessary. Unless specifically instructed otherwise by a physician, it is not required to be taken every day. You may take one pill per day at most, or as prescribed by your physician. The recommended dosage for benign prostate hyperplasia will vary depending on your doctor’s prescription. Never take more than the recommended or required dosage.

There are various unfavorable side effects of overdosing that could be lethal.

The beginning dose for ED is 20 mg. It may be changed as per your need. 

How Long Does it Take for Snovitra to Work?

Snovitra begins to work after roughly 30 to 60 minutes. It needs sexual stimulation to work effectively. It might even be a little bit longer in some circumstances. Therefore, it is preferable to wait a little longer if you are a first-time user.

How Long Does Snovitra Last?

Snovitra lasts for 5 to 6 hours after taking it. Incorrect dose or overdosing can frequently make a drug’s effects last longer than the normal duration.

What’s the Cost of Snovitra?

Snovitra costs about $0.24 per 20mg tablet. It is less compared to other more expensive brands of ED medications. 

Who Can Take Snovitra?

Snovitra is for men who have erectile dysfunction (ED). Most men who are over 18 years old can use this drug. However, it is best to go for a checkup with your physician first and adhere to their directions if you have any heart issues or are taking any long-term drugs. Children and women, especially those who are pregnant or nursing, should not use it.

The History of Snovitra

In 1989, it was discovered that the “wonder medication” sildenafil could lessen ED signs and symptoms. After then, research to create alternative ED medications started. The German business Bayer Pharmaceuticals revealed in 2001 that a different PDE5 inhibitor it was studying was equally successful in treating ED. Vardenafil was the medication. Following the patenting of this drug, Bayer and Glaxo Smith started producing it.

In 2003, the FDA approved the use of vardenafil for ED. In 2018, the patent on it expired. Since then, it has been produced at a reduced cost by various pharmaceutical companies.

Following the end of its patent, Parex Pharmaceuticals started producing Snovitra. Since then, this company has exported Snovitra to most countries in the world. 

How Does Snovitra Work?

An erection typically occurs when a man is sexually excited. Nitric Oxide (NO) is released from blood vessels and nerve terminals as a result of this sexual stimulation because it activates pelvic nerve signals. Cyclic guanosine monophosphate (cGMP) is released as a result of this NO release. Vascular dilatation brought on by cGMP increases blood flow to the penis. This causes the penis to enlarge and become erect. By holding blood inside the penis, the tunica albuginea maintains the penis’ erect position until the sexual contact is over.

Blood vessel dilation is prevented by phosphodiesterase Type 5 (PDE5), which is present in the corpora cavernosa, vascular smooth muscles, visceral smooth muscles, and platelets. In addition, the blood vessels themselves are typically impacted in ED patients.

The PDE5 inhibitor Snovitra prevents this enzyme’s activity in the penis, enabling blood flow and erectile function. It allows maximum blood flow in the penis, causing the erectile tissues to become engorged and thus, become erect. 

However, Snovitra cannot produce an erection on its own. To function, it requires sufficient sexual stimulation.

How Safe is Snovitra?

Most men can safely utilize Snovitra. It has proven to be beneficial even in individuals with ED brought on by a variety of systemic diseases. However, Snovitra has an overall impact on the human body like the majority of drugs do. Thus, it may have some negative effects. Most of them are mild, but some of them might be harmful. These negative effects are frequently brought about by either overdosing or using the improper dosage. Here, we’ll discuss Snovitra’s adverse effects.

Side Effects of Snovitra

Here are some of the common side effects reported by men who have taken Snovitra:

• Abdominal pain
• Abnormal vision
• Back pain
• Chest pain
• Cough
• Dry mouth
• Facial swelling
• Headaches
• Hot flushes
• Loss of hearing
• Muscle pain
• Nasal blockage
• Nausea
• Prolonged and painful erection
• Rash
• Sensitivity to light
• Tingling sensation in extremities

Medications That Can Interact With Snovitra

Snovitra and some drugs can interact, which may have unfavorable effects. The majority of these are blood pressure and cardiac medicines. So let your doctor know in advance if you’re taking any of these medications. If you take medications that can react with Snovitra, most of the other ED medications may also react the same with your meds as they all have a similar mechanism of action. 

The following medicines may interact with Snovitra:

Nitrates 

By increasing blood flow to the heart muscle and widening the heart’s blood channels, nitrates can reduce the strain on the heart. Hence they are called vasodilators. They are thus utilised to treat cardiac diseases including angina and coronary artery disease. Snovitra may interact with these drugs and significantly reduce blood pressure. Amyl nitrate, nitroglycerin, isosorbide, nitroprusside, and other drugs are examples of nitrates.

Alcohol

Snovitra users should refrain from consuming any alcohol because it could cause a sudden drop in blood pressure after rising from a sitting or standing position. Several PDE5 inhibitors, including Snovitra, have been shown to lower blood pressure when combined with alcohol and can produce side effects such as headaches, vomiting, dizziness, and low blood pressure.

Guanylate Cyclase Stimulators

Snovitra can reduce blood pressure when combined with these medicines. These include drugs like riociguat, which is typically advised for the treatment of pulmonary hypertension.

CYP3A4 Blockers

The liver’s CYP3A4 enzyme metabolizes the principal Snovitra ingredient, vardenafil. Inhibitors of the CYP3A4 enzyme stop it from working. Therefore, using Snovitra combined with CYP3A4 inhibitors may prolong the body’s elimination of the latter.  Consequently, Snovitra’s effects will last longer than they should. This may lead to certain unpleasant side effects due to the drug’s protracted effects. Ritonavir, ketoconazole, itraconazole, erythromycin, and other drugs are CYP34A inhibitors.

Anti-Hypertensives

Anti-hypertensive medications are used to treat hypertension. These medications and Snovitra might interact, leading to a severe reduction in blood pressure. Alpha-blockers, ACE inhibitors, calcium channel blockers, and angiotensin II receptor blockers are a few of these drugs.

CYP3A4 Inducers

These drugs oppose the effects of CYP3A4 inhibitors. They shorten Snovitra’s half-life by accelerating the drug’s metabolism in the body. The medication will have incomplete effects if it leaves the body earlier than expected. Examples of medications that induce CYP3A4 include phenobarbital, phenytoin, carbamazepine, rifampin, and other medicines.

Antacids

Snovitra’s effectiveness can be decreased by antacids because they reduce the body’s ability to absorb them. As a result, Snovitra won’t be able to work as intended in the system for a sufficient amount of time. Antacids include Alternagel, Amphojel, Alka-Seltzer, Tums, Magnesium hydroxide, Gelusil, Maalox, Mylanta, and Rolaids.

Who Should Not Use Snovitra?

There are certain conditions where Snovitra should not be used. These are:

• Patients diagnosed with retinitis pigmentosa
• Patients taking any of the contraindicated medications listed in the previous section
• Patients with a history of NAION or “crowded” optic disc
• Patients with a history of priapism
• Patients with certain blood disorders (haemophilia, leukaemia, sickle-cell anaemia)
• Patients with hypersensitivity to Snovitra
• Patients with severe heart disease or heart valve failure
• Patients with severe kidney disease

Medical Research Involving Snovitra

Some research shows that the active ingredient in Snovitra, vardenafil, is successful in treating ED [1]. It has additionally been demonstrated to help treat benign prostate hyperplasia [2]. Studies on this medicine from the specific company, however, are scant. This is so because the majority of businesses employ the same formula and manufacturing process to create the medicine. They, therefore, have little need to undertake their study.

Are There Any Alternatives to Snovitra?

There are many drugs available to treat ED. The majority are approved prescription medications that might include the same chemical as Snovitra. Therefore, it could be a good idea for you to explore it a little.

Pharmaceutical Alternatives

The drug Snovitra is a generic version. There are numerous additional drugs produced by different companies that function similarly to this one. Some of them might be expensive, while others might be more affordable.

 Here are some of the alternatives for Snovitra

• Sildenafil (Viagra, Cenforce, Kamagra, Fildena, P-Force, Vygex, & more)
• Tadalafil (Cialis, Adcirca, Vidalista, Tadacip, Forzest, & more)
• Avanafil (Avaforce, Stendra, Avana)
• Mirodenafil (Mvix)
• Udenafil (Zydena)
• Vardenafil (Levitra, Staxyn, Vilitra, Savitra, & more)

Natural Alternatives

The majority of these are traditional items about which little investigation has typically been done. If you are apprehensive to check out pharmaceutical medications, these might be an excellent place to start. If these natural remedies do not help you, you can always turn to prescription drugs.

The following are some drugs that could be used to treat ED:

Tongkat Ali —This herb can assist in treating ED [3]. It is believed to have aphrodisiac effects and may even improve fertility. It is said to have antiestrogen and pro-erectile effects. 

Ginseng (Panax ginseng) — Ginseng is a herb that has long been thought to be useful in treating ED. Ginseng consumption results in the generation of nitric oxide, which is thought to induce erections by calming the smooth muscles in the penis. The root may also boost energy levels and affect hormone regulation, which could heighten sexual excitement. [4].

Horny goat weed (Epimedium spp.) — Icariin, an enzyme found in this plant, has PDE5 inhibition abilities similar to Snovitra.  Joint discomfort, impotence, and poor libido can all be treated with horny goat weed [5].

Catuaba (Trichilia catigua or Erythroxylum Catuaba) — ED and low libido may be treated with Catuaba [6]. Due to its aphrodisiac qualities, Catuaba can treat sexual dysfunction.

Yohimbe (Pausinystalia johimbe) — Yohimbe helps with ED and improves erections [7]. As a result, they might become more sexually active. Yohimbine impacts the body by blocking alpha-2 adrenergic receptors. Yohimbine helps with erectile dysfunction by blocking the receptors that prevent erections. It may cause the release of nitric oxide to occur more quickly. As a result, the blood vessels in the penis may dilate, leading to penile erections.

L-arginine — L-arginine generates nitric oxide. The production of cGMP, which supports ED, can therefore be aided by the NO [8]. As a result of improved blood flow to the penis, an erection may remain longer. It might also increase energy levels and aid in strengthening muscles.

Where to Buy Snovitra in 2022?

Most areas require a prescription to buy Snovitra. Once you have a physician’s prescription for Snovitra, you can purchase it. Once you have it, you can purchase it online or through a local pharmacy. The latter might be preferable because it is discrete and simple.

Therefore, Snovitra may be the greatest ED medicine for you if you’re looking for one.

References Cited

1. Markou, S., Perimenis, P., Gyftopoulos, K., Athanasopoulos, A., & Barbalias, G. (2004). Vardenafil (Levitra) for erectile dysfunction: a systematic review and meta-analysis of clinical trial reports. International journal of impotence research, 16(6), 470-478. 
2. Stief, C. G., Porst, H., Neuser, D., Beneke, M., & Ulbrich, E. (2008). A randomized, placebo-controlled study to assess the efficacy of twice-daily vardenafil in the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia. European urology, 53(6), 1236-1244. 
3. Kotirum, S., Ismail, S. B., & Chaiyakunapruk, N. (2015). Efficacy of Tongkat Ali (Eurycoma longifolia) on erectile function improvement: Systematic review and meta-analysis of randomised controlled trials. Complementary therapies in medicine, 23(5), 693-698. 
4. E. D. Andrade, A. A. D. Mesquita, J. D. A. Claro, P. M. D. Andrade, V. Ortiz, M. Paranhos, M. Srougi, and T. Erdogan, “Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction,” Asian Journal of Andrology, vol. 9, no. 2, pp. 241–244, 2007.
5. Liu, W. J., Xin, Z. C., Xin, H., Yuan, Y. M., Tian, L., & Guo, Y. L. (2005). Effects of icariin on erectile function and expression of nitric oxide synthase isoforms in castrated rats. Asian journal of andrology, 7(4), 381-388.
6. P. H. C. Lim, “Asian herbals and aphrodisiacs used for managing ED,” Translational Andrology and Urology, vol. 6, no. 2, pp. 167–175, 2017.
7.  M. P. Carey and B. T. Johnson, “Effectiveness of yohimbine in the treatment of erectile disorder: Four meta-analytic integrations,” Archives of Sexual Behavior, vol. 25, no. 4, pp. 341–360, 1996.
8. Melman, A. (1997). L-Arginine and penile erection. The Journal of urology, 158(3), 686-686.