Tadalista Super Active

Tadalista Super Active is commonly prescribed for erectile dysfunction. Erectile dysfunction is a condition in which a man cannot achieve an erection adequate for complete sexual intercourse. It also impacts a couple’s personal life and mental health.

So, a drug that improves erection does not only improve sexual satisfaction but also benefits in terms of improving interpersonal relationships and mental health.

In this article, we will try to give a brief explanation of the drug. The explanation includes the dose of the medicine, how fast it acts, and how long it lasts. We would also explain how the drug works when avoiding consumption, what the other uses are, and the drug interactions.

What is Tadalista Super Active?

Tadalista Super Active is based on the ingredient tadalafil, which is also used in the well-known brand Cialis. It is also used for the treatment of symptoms associated with benign prostatic hyperplasia. All the medicines related to the Tadalista band name are manufactured by Fortune Healthcare Private Limited.

The medicine is available in the form of soft gel capsules. Soft gel capsules are capsules containing a liquid form of the drug covered by a gelatinous soluble covering. After intake, the outer covering dissolves instantaneously, resulting in the release of liquid inside, which is absorbed faster. So, soft gel capsules work faster than film-coated oral tablets.

Tadalista Super Active is a form of phosphodiesterase 5 inhibitor. So, it works by improving the blood flow to the penis with minimal side effects compared to other medications with similar action like Viagra (sildenafil). However, the medicine only works if sexual stimulation is already present.

The medicine must be taken as prescribed by the doctor, and you must provide information regarding your medical history and information about all the medications that you are currently taking.

What’s the Dose of Tadalista Super Active?

Tadalista Super Active comes in a soft gel capsule with a dose of 20 mg. However, other products with the name Tadalista are available in the following dosages:

Tadalista 10 mg
Tadalista 20 mg
Tadalista 40 mg
Tadalista 60 mg
Tadalista 5 mg
Tadalista CT 20 mg

For erectile dysfunction (ED), Tadalista Super Active is taken on an “as needed” basis as prescribed. It should not be taken for sexual arousal or adventure.

The maximum dose of Tadalista Super Active for ED is 1 pill per day. The drug should be taken with a full glass of water, and you should follow your doctor’s instructions regarding medicine consumption.

How Long Does Tadalista Super Active Last?

The half-life of Tadalista Super Active is 17.5 hours, and its activity lasts for around 36 hours. After consuming it, it begins to work within 30 minutes.

The drug owes its long duration to the slow half-life of the active ingredient. It takes roughly 17.5 hours for exactly half of the drug to be metabolized. Compare this to 4 hours with Viagra. The drug is also known as the “weekend pill,” as the effect of the drug lasts for a weekend.

How Much Does Tadalista Super Active Cost?

The cost of Tadalista Super Active is variable and depends on the dose. The cost of the tablet is somewhere around $0.81 to $0.85 per pill.

The generic drug tadalafil is also available as a less expensive choice, depending on the situation.

The History of Tadalista Super Active

In August 1991, Tadalafil was discovered under a partnership between Glaxo and ICOS to develop a new drug. In 1998, ICOS Corporation and Eli Lilly and Company formed Lilly ICOS, LLC, a joint venture company to further develop and commercialize tadalafil as a treatment for ED. [1]

A new drug application for Tadalafil, which goes by the brand name Cialis, was submitted to the FDA by Lilly ICOS, LLC two years later. In 2003, the FDA approved tadalafil for the treatment of erectile dysfunction (ED). In 2011, the FDA approved the use of tadalafil for signs and symptoms of benign prostatic hyperplasia (BPH).

The FDA has also approved tadalafil for the treatment of both BPH and erectile dysfunction (ED), where the two conditions co-exist. Tadalista Super Active is used as a brand name for tadalafil. Tadalafil is no longer protected under patent. So, the generic form is available under various brand names.

Who Should Take Tadalista Super Active?

Tadalista Super Active is to treat erectile dysfunction (ED). Tadalafil in the lower dosage is also used for treating signs and symptoms of prostatic enlargement.

In and of itself, Tadalista Super Active is not a sexual stimulant. Other strategies for increasing erection and arousal, such as regular exercise, a healthy diet, plenty of fluids, stress management, abstaining from alcohol and tobacco, and foreplay before sexual activity, should also be followed. Additionally, Tadalista Super Active does not safeguard you against STDs.

Your doctor will weigh the benefits of the drug against your level of risk. They’ll assess your current medications to see if any potential drug interactions would prevent you from being able to safely use the drug.

Is Tadalista Super Active Safe?

There are some side effects, even though Tadalista Super Active is typically regarded as a safe and reliable medication. Rarely, severe side effects may occur.

The most common side effects reported were headaches, dyspepsia, back pain, nasal congestion, myalgia, and flushing. [2] These side effects are usually mild and go away after a certain period. If they become severe or persist, inform your doctor.

However, there are a few side effects that can be potentially serious and can lead to debilitating outcomes. You need to consult your doctor immediately if you develop any of these side effects:

Sudden loss of heating
Ringing sensation in the ear.
Sudden loss of vision
Vision problems like difficulty differentiating between blue and green colors
Palpitation
Shortness of breath
Seizure
Lightheadedness
Symptoms of a heart attack such as chest pain, nausea, difficulty in breathing, sweating
Painful erections or prolonged erections (erections lasting for more than 4 hours)
Symptoms related to an allergy to any of the ingredients such as itching, difficulty breathing, rashes, swelling of the face or lips, and hoarseness of voice.

Tadalista Super Active Drug Interactions

Below is a list of medications that can interact with Tadalista Super Active. Not all medications that could interact with Tadalista Super Active are included in this list.

Consult your doctor and pharmacist before taking Tadalista Super Active. All prescription, over-the-counter, and other medications you take should be disclosed to them. Additionally, let them know if you take any vitamins, herbs, or supplements. Sharing this information can help you avoid potential interactions.

Some common drugs that may interact with Tadalista Super Active include:

Nitrates

Nitrates are used for the treatment of chest pain in angina. Taking nitrates along with Tadalista Super Active can seriously lower blood pressure, leading to heart attack or stroke. [3]

Alpha-Blockers

Both Tadalista Super Active and alpha-blockers are vasodilators that have the potential to lower blood pressure below normal ranges.

Antihypertensives

Both medications lead to a lowering of blood pressure. As a result, you must tell your doctor if you are taking any antihypertensive drugs.

Alcohol

Tadalista Super Active and alcohol interactions can result in low blood pressure, headaches, dizziness, and an accelerated heart rate. It might also affect the efficacy of Tadalista Super Active.

Antacids

If you’re taking Tadalista Super Active and using antacids to treat heartburn, the antacids may decrease the level of Tadalista Super Active that your body absorbs. This implies that Tadalista Super Active may not be administered in its entirety, which could result in less effective treatment of your ED or BPH symptoms.

CYP3A4 Inhibitors

Tadalista Super Active is primarily metabolized in the liver by the CYP3A4 enzymes. The rate of decay for Tadalista Super Active can be impacted by taking additional medications that are metabolized by this enzyme. As a result, the drug may have a longer half-life and have higher bloodstream concentrations. This can increase the risk of developing side effects.

Common CYP3A4 inhibitors include:

Sodium valproate
Isoniazid
Cimetidine
Ketoconazole
Omeprazole

CYP3A4 Inducers

Contrary to CYP3A4 inhibitors, some drugs boost this enzyme’s activity, causing Tadalista Super Active to be metabolized more quickly. This may reduce the effectiveness of the medicine.

Common CYP3A4 inducers include:

Rifampin
Carbamazepine
Phenytoin
Phenobarbital
Griseofulvin

Who Should Avoid Taking Tadalista Super Active?

Tadalista Super Active should be avoided by patients with:

Known intolerances to tadalafil, including Tadalista Super Active.
Pulmonary hypertension
Uncontrolled high or low blood pressure
Chronic liver or kidney disease
Retinitis pigmentosa
A history of NAION (Non-arteritic anterior ischemic optic neuropathy)
Current stomach ulcers
Peyronie’s disease

How Does Tadalista Super Active Work?

When a person has erectile dysfunction, they are unable to get or keep an erection. Erection occurs when smooth muscles in the penis relax, causing blood flow in the penis. Guanylyl cyclase activity is increased by nitric oxide, which raises the concentration of cyclic guanosine monophosphate (cGMP). The chemical cGMP in your body relaxes the penis muscles and improves blood flow to the penis. If you have ED, you cannot achieve or maintain an erection because this activity isn’t functioning properly.

Tadalista Super Active works by inhibiting an enzyme called phosphodiesterase 5. The enzyme is in charge of metabolizing cGMP and bringing down its concentration. As a result, blocking this enzyme raises blood levels of cGMP, which relaxes smooth muscle and increases blood flow to the penis, resulting in penile erection.

The signal to the penis that initiates the erection still needs to be sent during arousal. Therefore, Tadalista Super Active only functions when there is sexual arousal.

Can Women Use Tadalista Super Active Too?

Since erectile dysfunction and benign prostatic hyperplasia are both male-specific health conditions, Tadalista Super Active is not approved for use in women.

Tadalista Super Active improves blood flow to the penis by blocking the action of an enzyme called PDE5. This enzyme is also found in the vagina and the clitoris of women. So, in theory, if a woman takes Tadalista Super Active, it could increase blood flow to her genitals, but the amount of PDE5 found in women is less than that of men. So, studies have not shown enough evidence to suggest the use of Tadalista Super Active in women.

Also, sexual problems in women often have a lot to do with reduced sexual desire and arousal. These problems are unlikely to be resolved by Tadalista Super Active. [4]

Tadalista Super Active Alternative

There are numerous branded PDE5 inhibitors used to treat erectile dysfunction, Tadalista Super Active being just one of them.

Some pharmaceutical alternatives to Tadalista Super Active include:

Sildenafil (Viagra)
Vardenafil (Levitra, Staxyn, and Vivanza)
Avanafil (Stendra)
Mirodenafil (Mvix)
Udenafil (Zydena)

Additionally, since Tadalista Super Active is no longer covered by a patent, generic versions of the medication are easily accessible and considerably less expensive than the licensed brand-name version.

Tadalista Super Active Natural Alternatives

Nothing in the natural world is as dependable as Tadalista Super Active or other prescription medications, despite the existence of natural PDE5 inhibitors and other erectile dysfunction supplements.

Many of these natural ingredients lack the clinical testing and ethical approval required to ethically recommend these products for use.

However, there are a few promising candidates worth mentioning:

Horny Goat Weed (Epimedium spp.)—this plant contains a compound called icariin, which is a relatively strong PDE5 inhibitor similar to Tadalista Super Active.

L-Arginine: This amino acid is one of the required precursors for nitric oxide production, which in turn promotes the activity of cGMP to promote erection.

Korean Red Ginseng (Panax quinquefolium)—KRG extracts have been shown to improve nitric oxide production, promote dilation of the arteries in the penis, and promote erection.

Where to Buy Tadalista Super Active?

Tadalista Super Active is a prescription-only medication. It indicates that you can only purchase it with a valid doctor’s prescription from a pharmacy or online drug store.

You must tell the doctor about your medical condition and any medicines, herbs, or supplements that you are taking. The doctor may also evaluate your general health and, if necessary, order some investigations.

The doctor would then decide whether or not to prescribe the medication.

References Used

Daugan, A., Grondin, P., Ruault, C., Le Monnier de Gouville, A. C., Coste, H., Linget, J. M., … & Labaudinière, R. (2003). The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2, 3, 6, 7, 12, 12a-hexahydropyrazino [1 ‘, 2 ‘: 1, 6] pyrido [3, 4-b] indole-1, 4-dione analogues. Journal of medicinal chemistry, 46(21), 4533-4542.\
Frajese, G. V., Pozzi, F., & Frajese, G. (2006). Tadalafil in the treatment of erectile dysfunction; an overview of the clinical evidence. Clinical interventions in aging, 1(4), 439.
Kloner, R. A., Hutter, A. M., Emmick, J. T., Mitchell, M. I., Denne, J., & Jackson, G. (2003). Time course of the interaction between tadalafil and nitrates. Journal of the American College of Cardiology, 42(10), 1855-1860.
Monte, G. L., Graziano, A., Piva, I., & Marci, R. (2014). Women taking the “blue pill”(sildenafil citrate): such a big deal?. Drug Design, Development and Therapy, 8, 2251.