Vigore is a medication that treats erectile dysfunction by increasing blood flow to the penis. Vigore is unique in that it contains sildenafil citrate as its active ingredient, which is also found in the popular medication Viagra. 

In this article, we will explore what Vigore is, how it works, its potential side effects, and the differences between Vigore and other ED medications, providing a comprehensive guide to help individuals make informed decisions about their sexual health.

What is Vigore?

Vigore is manufactured by Zydus Cadila and it is designed to treat erectile dysfunction (ED). It has become increasingly popular in recent years due to its effectiveness in improving sexual health. Its active ingredient is sildenafil citrate, identical to that of the well-known medication Viagra. Vigore has similar results at a potentially lower cost. 

This makes Vigore a more cost-effective alternative to Viagra while providing the same potential benefit of improved sexual performance. Additionally, Vigore may come in different forms, such as tablets and oral jelly, providing flexibility for individuals in terms of how they choose to take the medication.

What’s The Dose Of Vigore?

The appropriate dose of Vigore can vary depending on the individual’s age, medical history, and the severity of the condition being treated. In general, the recommended starting dose for most individuals is 50 mg taken orally approximately 1 hour before sexual activity. 

However, the dose may be adjusted up to 100 mg or down to 25 mg based on an individual’s response and tolerance to the medication. It is important to note that Vigore should not be taken more than once a day, and individuals should not exceed the recommended dose without consulting their healthcare provider.

How Long Does Vigore Take To Kick In?

The time it takes for Vigore to start working can vary depending on several factors, such as an individual’s age, medical history, and whether the medication is taken with or without food. In general, Vigore is typically absorbed quickly and begins to work within 30 to 60 minutes of taking the medication orally. 

However, it is important to note that sexual stimulation is necessary for Vigore to work effectively, as the medication works by increasing blood flow to the penis to help achieve and maintain an erection. It is essential to follow the recommended dosing instructions and talk to a healthcare provider if Vigore does not seem to be working effectively or if any adverse effects occur.

How Long Does Vigore Last?

The duration of action for Vigore can vary depending on several factors, such as an individual’s age, medical history, and dosage. In general, the effects of Vigore can last for approximately 4 to 5 hours after taking the medication orally. 

However, the duration of the medication’s effectiveness can vary between individuals, and factors such as food intake and alcohol consumption may also affect how long the medication lasts. It is important to note that Vigore should not be taken more than once in 24 hours. Individuals should seek medical attention if an erection lasts for more than 4 hours or if any other adverse effects occur.

How Much Does Vigore Cost?

The cost of Vigore can vary depending on several factors such as location, dosage strength, and the quantity purchased. In general, Vigore may be less expensive than other similar medications, such as Viagra, due to the availability of generic versions. 

The cost of generic sildenafil citrate can range from approximately $0.70 to $2.50 per tablet, while the branded version of Viagra can cost upwards of $65 per tablet. It is important to note that the cost of Vigore may not be covered by insurance, and individuals should check with their healthcare provider and insurance provider to determine the coverage and potential out-of-pocket costs associated with the medication.

Who Should Take Vigore?

Sildenafil citrate, an active ingredient in Vigore, is approved by the FDA to treat ED. It works by increasing blood flow to the penis, enabling an erection in response to sexual stimulation. Vigore is specifically designed for adult men who have difficulty achieving or maintaining an erection sufficient for sexual activity. However, it is important to note that Vigore is not a cure for ED, and does not increase sexual desire or protect against sexually transmitted infections. 

Vigore is also used off-label for the treatment of pulmonary arterial hypertension (PAH), a type of high blood pressure that affects the arteries in the lungs and heart. 

In addition, some studies have suggested that sildenafil citrate may have potential therapeutic benefits for conditions such as Raynaud’s phenomenon and altitude sickness. However, off-label use of sildenafil citrate should only be done under the guidance of a licensed healthcare professional, as it may carry risks and side effects.

Is Vigore Safe?

Vigore can be safe for individuals who have been prescribed it by a licensed healthcare professional and take it as directed. However, as with any medication, there are potential side effects and health risks associated with its use.

Common Side Effects of Vigore

Here are some common side effects of Vigore:

  • Headache
  • Flushing
  • Indigestion
  • Nasal congestion
  • Blurred vision
  • Dizziness
  • Muscle or back pain
  • Nausea
  • Skin rash or itching
  • Diarrhea

Potential Drug Interactions With Vigore

Vigore can interact with certain medications, which may increase the risk of side effects or reduce the effectiveness of either medication. Here are some of the main medication classes that should be avoided or used with caution when taking Vigore:


Vigore should not be taken with nitrates, which are often used to treat chest pain or heart problems. Combining Vigore with nitrates can cause a sudden and serious decrease in blood pressure, which can be life-threatening.


Alpha-blockers are medications used to treat high blood pressure or prostate problems. Taking Vigore with alpha-blockers can cause a sudden drop in blood pressure, which can be dangerous.

Protease inhibitors: 

Protease inhibitors are a type of medication used to treat HIV and other viral infections. Taking Vigore with protease inhibitors can increase the risk of side effects or reduce the effectiveness of either medication.

Other medications for erectile dysfunction: 

Taking Vigore with other medications used to treat erectile dysfunction, such as tadalafil or vardenafil, can increase the risk of side effects or reduce the effectiveness of either medication.

Blood pressure medications: 

Certain medications used to treat high blood pressure, such as calcium channel blockers or beta-blockers, can interact with Vigore and cause a sudden drop in blood pressure.

It’s important to talk to your healthcare provider about all medications, supplements, and herbal products you are taking before starting Vigore to avoid potential drug interactions.

Who Should Avoid Using Vigore?

  • Patients with severe heart disease or heart valve failure
  • Patients with a history of NAION or “crowded” optic disc
  • Patients diagnosed with retinitis pigmentosa
  • Patients taking any of the contraindicated medications listed in the previous section
  • Patients with a history of Vigore hypersensitivity
  • Patients with a history of priapism
  • Patients with severe kidney disease
  • Patients with certain blood disorders (hemophilia, leukemia, sickle-cell anemia)

How Does Vigore Work?

Let’s dig into the basic physiology of erection before we discuss how Vigore works.  Phosphodiesterase type 5 (PDE5) is an enzyme responsible for breaking down a chemical called cyclic guanosine monophosphate (cGMP) in the penis. cGMP relaxes the smooth muscle in the penis. This increases the blood flow into the penis and causes an erection. 

Vigore is a PDE5 inhibitor. By inhibiting PDE5, it increases the levels of cGMP. This leads to improved blood flow to the penis and improves erectile function.

It’s important to keep in mind that Vigore does not enhance sexual desire or libido. Sexual stimulation is essential for its effectiveness. Additionally, its efficacy may be influenced by factors such as food, alcohol, and other medications, and it may take some time to take effect. Vigore should only be used as instructed by a licensed healthcare professional.

Medical Research Involving Vigore

As a generic medication, there may not be specific research available for Vigore itself, as it is essentially a copy of the brand name medication Viagra, which has been extensively researched. Generic medications can be produced by copying the formula of the brand name medication once its patent expires. As a result, there is often little incentive for generic manufacturers to conduct their research on the medication.

However, the brand name medication Viagra has been extensively studied in clinical trials and has been approved by regulatory agencies such as the U.S. Food and Drug Administration (FDA) for the treatment of erectile dysfunction. Some of the key studies on Viagra have demonstrated its effectiveness in improving erectile function in men with various underlying medical conditions, such as diabetes, hypertension, and spinal cord injury [1, 2].

Best Vigore Alternatives

There are many medications available for the treatment of erectile dysfunction. While Vigore is a commonly prescribed medication in this class, there are several other options available as well. Some of these medications use the same active ingredient as Vigore, while others use different ingredients that work in a similar way to improve blood flow to the penis and improve erection. 

Pharmaceutical Alternatives

Vigore is a generic medication, which means that it is manufactured by many different pharmaceutical companies. These companies may use different brand names for their versions of the medication, but they will all contain the same active ingredient and be the same dose. As a result, there are many pharmaceutical alternatives to Vigore available on the market, which may be sold at different prices and may have different brand names. Here are a few examples of alternative medications that may be prescribed for erectile dysfunction:

  • Sildenafil (Viagra, Cenforce, Kamagra, Fildena, P-Force, Vygex, & more)
  • Tadalafil (Cialis, Adcirca, Vidalista, Tadacip, Forzest, & more)
  • Avanafil (Avaforce, Stendra, Avana)
  • Mirodenafil (Mvix)
  • Udenafil (Zydena)
  • Vardenafil (Levitra, Staxyn, Vilitra, Zhewitra, Savitra, & more)

Natural Vigore Alternatives

It is equally important to remember that there are some herbs and nutrients that can also help facilitate erection. These are better to start with than prescription medications. If these don’t work, it is better to move up to pharmaceutical options. Here are some natural alternatives to Vigore:

Horny goat weed (Epimedium spp.)

Horny goat weed is a Chinese herb used to treat erectile dysfunction and increase libido. It contains a compound called icariin that acts similarly to Viagra by increasing blood flow to the penis [3].

Ginseng (Panax ginseng)

Ginseng is a popular herb used to increase energy levels, reduce stress, and improve sexual function. It works by improving blood flow and increasing nitric oxide levels, which can help improve erectile dysfunction [4].

Muira puama (Ptychopetalum olacoides)

Muira puama is a Brazilian plant commonly used to increase libido and treat erectile dysfunction. It works by increasing blood flow and stimulating the nervous system [5].


L-Arginine is an amino acid that is naturally produced in the body and is commonly used as a dietary supplement. It helps to increase nitric oxide levels, which can improve blood flow and help with erectile dysfunction [6].

Catuaba (Trichilia catigua or Erythroxylum catuaba)

Catuaba is a Brazilian plant commonly used to treat impotence and increase libido. It works by stimulating the nervous system and increasing blood flow [7].

Yohimbe (Pausinystalia johimbe)

Yohimbe is a tree native to Central and West Africa, and its bark contains a compound called yohimbine, which is used to treat erectile dysfunction. It works by increasing blood flow to the penis [8].

Tribulus (Tribulus terrestris)

Tribulus is a plant commonly used to increase testosterone levels and improve sexual function. It works by increasing nitric oxide levels and improving blood flow [9].

Pine Pollen (Pinus spp.)

Pine pollen is a natural supplement commonly used to increase energy levels and improve sexual function. It contains various nutrients that can help increase testosterone levels and improve erectile function [10].

While there are natural alternatives available, it’s essential to note that their efficacy may vary, and it’s always advisable to consult a healthcare professional before using any natural supplements. It’s important to note that they may also interact with other medications or have side effects.

Where to Buy Vigore in 2023?

Vigore is a prescription medication and can only be bought with a recommendation from a doctor. Local pharmacies are the primary sources for purchasing the drug, but for those who desire convenience and privacy, online purchasing is a popular alternative. Buying Vigore online can also be cost-effective as online sellers may offer discounts, promotions, or bulk pricing. 

Online purchasing provides convenience and privacy, especially for individuals who are uncomfortable discussing their condition in a person or have difficulty accessing physical pharmacies. 

Despite that, it is important to be cautious and only purchase from reputable and trustworthy online pharmacies to avoid purchasing counterfeit or substandard products that can be dangerous to your health. Please note that online purchasing does not replace regular check-ups with healthcare professionals. 

In summary, while buying Vigore in person may be suitable for some, online purchasing can provide a more cost-effective and discreet option for those who have a prescription and choose to buy from reputable online sources.

References Cited in This Article

  1. Goldstein, I., Lue, T. F., Padma-Nathan, H., Rosen, R. C., Steers, W. D., & Wicker, P. A. (1998). Oral sildenafil in the treatment of erectile dysfunction. New England Journal of Medicine, 338(20), 1397-1404.
  2. Shinlapawittayatorn, K., Chattipakorn, S., & Chattipakorn, N. (2005). Effect of sildenafil citrate on the cardiovascular system. Brazilian journal of medical and biological research, 38, 1303-1311.
  3. Liu, W. J., Xin, Z. C., Xin, H., Yuan, Y. M., Tian, L., & Guo, Y. L. (2005). Effects of icariin on erectile function and expression of nitric oxide synthase isoforms in castrated rats. Asian journal of andrology, 7(4), 381-388.
  4. De Andrade, E., De Mesquita, A. A., de Almeida Claro, J., De Andrade, P. M., Ortiz, V., Paranhos, M., … & Erdogrun, T. (2007). Study of the efficacy of Korean Red Ginseng in the treatment of erectile dysfunction. Asian journal of andrology, 9(2), 241-244.
  5. Ferrini, M. G., Garcia, E., Abraham, A., Artaza, J. N., Nguyen, S., & Rajfer, J. (2018). Effect of ginger, Paullinia cupana, muira puama and l-citrulline, singly or in combination, on modulation of the inducible nitric oxide-NO-cGMP pathway in rat penile smooth muscle cells. Nitric Oxide, 76, 81-86.
  6. Moody, J. A., Vernet, D., Laidlaw, S., Rajfer, J., & Gonzalez-Cadavid, N. F. (1997). Effects of long-term oral administration of L-arginine on the rat erectile response. The journal of urology, 158(3), 942-947.
  7. Lim, P. H. (2017). Asian herbals and aphrodisiacs used for managing ED. Translational andrology and urology, 6(2), 167.
  8. Carey, M. P., & Johnson, B. T. (1996). Effectiveness of yohimbine in the treatment of erectile disorder: Four meta-analytic integrations. Archives of sexual behavior, 25(4), 341-360.
  9. Zhang, H., Tong, W. T., Zhang, C. R., Li, J. L., Meng, H., Yang, H. G., & Chen, M. (2019). Gross saponin of Tribulus terrestris improves erectile dysfunction in type 2 diabetic rats by repairing the endothelial function of the penile corpus cavernosum. Diabetes, metabolic syndrome and obesity: targets and therapy, 1705-1716.
  10. Robertson, N. U., Schoonees, A., Brand, A., & Visser, J. (2020). Pine bark (Pinus spp.) extract for treating chronic disorders. Cochrane Database of Systematic Reviews, (9).







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